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Physical activity and prostate cancer in the Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study (Finland)
Author(s): Hartman TJ, Albanes D, Rautalahti M, Tangrea JA, Virtamo J, Stolzenberg R, Taylor PR
Source: CANCER CAUSES & CONTROL    Volume: 9    Issue: 1    Pages: 11-18    Published: JAN 1998  
Times Cited: 43     References: 49     
Abstract: The association between physical activity and prostate cancer was evaluated in the trial-based cohort of the Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study (n = 29,133). During up to nine years of follow-up, 317 men developed incident prostate cancer. The relationship between occupational, leisure, and combined activity and prostate cancer was assessed in multivariate Cox regression models that adjusted for intervention group, benign prostatic hyperplasia, age, smoking, and urban residence. Compared with sedentary workers, relative risks (RR) and 95 percent confidence intervals (CI) for occupational walkers, walker/lifters, and heavy laborers were 0.6 (CI = 0.4-1.0), 0.8 (CI = 0.5-1.3), and 1.2 (CI = 0.7-2.0), respectively. Among working men, leisure activity (active cf sedentary) was associated inversely with risk (RR = 0.7, CI = 0.5-0.9). This inverse association for leisure activity was observed, with the exception of heavy laborers, for all occupational activity levels, and was strongest among walkers compared with men sedentary at work and leisure, and to a lesser degree among walker/lifters. These results are consistent with a protective effect of physical activity on prostate cancer.
Document Type: Article
Language: English
Reprint Address: Hartman, TJ (reprint author), NCI, Div Clin Sci, Execut Plaza N,Suite 211,6130 Execut Blvd MSC 732, Bethesda, MD 20892 USA
Addresses:
1. NCI, Div Clin Sci, Bethesda, MD 20892 USA
2. Natl Publ Hlth Inst, Helsinki, Finland
Publisher: KLUWER ACADEMIC PUBL, SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS
Subject Category: Oncology; Public, Environmental & Occupational Health
IDS Number: YV685
ISSN: 0957-5243
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