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| The complete genome of the hyperthermophilic bacterium Aquifex aeolicus |
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| Author(s): Deckert G, Warren PV, Gaasterland T, Young WG, Lenox AL, Graham DE, Overbeek R, Snead MA, Keller M, Aujay M, Huber R, Feldman RA, Short JM, Olsen GJ, Swanson RV |
| Source: NATURE Volume: 392 Issue: 6674 Pages: 353-358 Published: MAR 26 1998 |
| Times Cited: 716 References: 49 |
| Abstract: Aquifex aeolicus was one of the earliest diverging, and is one of the most thermophilic, bacteria known. It can grow on hydrogen, oxygen, carbon dioxide, and mineral salts. The complex metabolic machinery needed for A. aeolicus to function as a chemolithoautotroph (an organism which uses an inorganic carbon source for biosynthesis and an inorganic chemical energy source) is encoded within a genome that is only one-third the size of the E, coli genome, Metabolic flexibility seems Po be reduced as a result of the limited genome size, The use of oxygen (albeit at very low concentrations) as an electron acceptor is allowed by the presence of a complex respiratory apparatus. Although this organism grows at 95 degrees C, the extreme thermal limit of the Bacteria, only a few specific indications of thermophily are apparent from the genome. Here we describe the complete genome sequence of 1,551,335 base pairs of this evolutionarily and physiologically interesting organism. |
| Document Type: Article |
| Language: English |
| Reprint Address: Swanson, RV (reprint author), Diversa Corp, 10665 Sorrento Valley Rd, San Diego, CA 92121 USA |
Addresses:
1. Diversa Corp, San Diego, CA 92121 USA
2. Argonne Natl Lab, Div Math & Comp Sci, Argonne, IL 60439 USA
3. Univ Illinois, Dept Microbiol, Urbana, IL 61801 USA
4. Univ Regensburg, Lehrstuhl Mikrobiol, D-8400 Regensburg, Germany |
| Publisher: MACMILLAN MAGAZINES LTD, PORTERS SOUTH, 4 CRINAN ST, LONDON, ENGLAND N1 9XW |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: ZD694 |
| ISSN: 0028-0836 |
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