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| Abnormal erythropoiesis in erythroleukemia: A fluorescence in situ hybridization study |
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| Author(s): Wong KF, Chu YC, Kwong YL |
| Source: CANCER GENETICS AND CYTOGENETICS Volume: 105 Issue: 2 Pages: 187-189 Published: SEP 1998 |
| Times Cited: 2 References: 8 |
| Abstract: Erythroleukemia is an uncommon leukemia with heterogeneous morphologic and karyotypic features. Some cases might actually represent acute myeloid leukemia with a reactive erythroid hyperplasia. In this report, we described a 68-year-old woman with erythroleukemia and monosomy 7 and showed by fluorescence in situ hybridization that both myeloid and erythroid lineage were clonally involved and that both normal and abnormal erythroid populations coexisted, albeit indistinguishable by morphological examination. These findings may account for the variation in the erythropoietic activity observed in the clinical course of erythroleukemia. (C) Elsevier Science Inc., 1998 |
| Document Type: Article |
| Language: English |
| Reprint Address: Wong, KF (reprint author), Queen Elizabeth Hosp, Dept Pathol, 30 Gascoigne Rd, Kowloon, Hong Kong |
Addresses:
1. Queen Elizabeth Hosp, Dept Pathol, Kowloon, Hong Kong
2. Queen Elizabeth Hosp, Dept Med, Kowloon, Hong Kong
3. Queen Mary Hosp, Dept Med, Hong Kong, Peoples R China |
| Publisher: ELSEVIER SCIENCE INC, 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 USA |
| Subject Category: Oncology; Genetics & Heredity |
| IDS Number: 111TA |
| ISSN: 0165-4608 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |