| | |  | | | | Record from Web of Science® | | | | | | |
| Death receptors: Signaling and modulation |
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| Author(s): Ashkenazi A, Dixit VM |
| Source: SCIENCE Volume: 281 Issue: 5381 Pages: 1305-1308 Published: AUG 28 1998 |
| Times Cited: 3,134 References: 89 |
| Abstract: Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors, on their surface. Death receptors detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. |
| Document Type: Review |
| Language: English |
| Reprint Address: Ashkenazi, A (reprint author), Genentech Inc, Dept Mol Oncol, 1 DNA Way, S San Francisco, CA 94080 USA |
Addresses:
1. Genentech Inc, Dept Mol Oncol, S San Francisco, CA 94080 USA |
| Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 USA |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: 115LQ |
| ISSN: 0036-8075 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |