| | |  | | | | Record from Web of Science® | | | | | | |
| Anti-hyperactivity medication: methylphenidate and amphetamine |
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| Author(s): Seeman P, Madras BK |
| Source: MOLECULAR PSYCHIATRY Volume: 3 Issue: 5 Pages: 386-396 Published: SEP 1998 |
| Times Cited: 123 References: 105 |
| Abstract: How do 'stimulants' reduce hyperactivity in children and adults? How can drugs which raise extracellular dopamine result in psychomotor slowing of hyperactive children when dopamine is known to enhance motor activity, such as in Parkinson's disease? These apparent paradoxes are the focus of this brief review on the mechanism of action of stimulant medications used in the treatment of children, and of an increasing number of adults who meet diagnostic criteria for attention deficit hyperactivity disorder. |
| Document Type: Review |
| Language: English |
| Reprint Address: Seeman, P (reprint author), Univ Toronto, Dept Pharmacol, Med Sci Bldg,Room 4344,8 Taddle Creek Rd, Toronto, ON M5S 1A8 Canada |
Addresses:
1. Univ Toronto, Dept Pharmacol, Toronto, ON M5S 1A8 Canada
2. Univ Toronto, Dept Psychiat, Toronto, ON M5S 1A8 Canada
3. Harvard Univ, New England Reg Primate Res Ctr, Sch Med, Dept Psychiat,Div Neurochem, Southborough, MA 01772 USA |
| Publisher: STOCKTON PRESS, HOUNDMILLS, BASINGSTOKE RG21 6XS, HAMPSHIRE, ENGLAND |
| Subject Category: Biochemistry & Molecular Biology; Neurosciences; Psychiatry |
| IDS Number: 118PZ |
| ISSN: 1359-4184 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |