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New goals for the US Human Genome Project: 1998-2003
Author(s): Collins FS, Patrinos A, Jordan E, Chakravarti A, Gesteland R, Walters L, Fearon E, Hartwelt L, Langley CH, Mathies RA, Olson M, Pawson AJ, Pollard T, Williamson A, Wold B, Buetow K, Branscomb E, Capecchi M, Church G, Garner H, Gibbs RA, Hawkins T, Hodgson K, Knotek M, Meisler M, Rubin GM, Smith LM, Smith RF, Westerfield M, Clayton EW, Fisher NL, Lerman CE, McInerney JD, Nebo W, Press N, Valle D
Source: SCIENCE    Volume: 282    Issue: 5389    Pages: 682-689    Published: OCT 23 1998  
Times Cited: 495     References: 8     
Abstract: The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-98. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, 2 years ahead of previous projections. In the course of completing the sequence, a "working draft" of the human sequence will be produced by the end of 2001. The plan also includes goals for sequencing technology development; for studying human genome sequence variation; for developing technology for functional genomics; for completing the sequence of Caenorhabditis elegans and Drosophila melanogaster and starting the mouse genome; for studying the ethical, Legal, and social implications of genome research; for bioinformatics and computational studies; and for training of genome scientists.
Document Type: Review
Language: English
Reprint Address: Collins, FS (reprint author), Natl Human Genome Res Inst, NIH, Bethesda, MD 20892 USA
Addresses:
1. Natl Human Genome Res Inst, NIH, Bethesda, MD 20892 USA
2. US DOE, Off Biol & Environm Res, Washington, DC 20585 USA
3. Case Western Reserve Univ, Dept Genet, Cleveland, OH 44106 USA
4. Case Western Reserve Univ, Ctr Human Genet, Cleveland, OH 44106 USA
5. Univ Hosp Cleveland, Cleveland, OH 44106 USA
6. Univ Utah, Howard Hughes Med Inst, Salt Lake City, UT 84112 USA
7. Georgetown Univ, Kennedy Inst Eth, Washington, DC 20057 USA
Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 USA
Subject Category: Multidisciplinary Sciences
IDS Number: 132AM
ISSN: 0036-8075
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