| | |  | | | | Record from Web of Science® | | | | | | |
| Growing evidence that several human cancers may originate in utero |
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| Author(s): Ekbom A |
| Source: SEMINARS IN CANCER BIOLOGY Volume: 8 Issue: 4 Pages: 237-244 Published: AUG 1998 |
| Times Cited: 48 References: 75 |
| Abstract: Hormone-related cancers may originate in utero. Accumulating evidence is given by animal studies, descriptive epidemiologic data and analytic etiologic studies. Indicators of high levels of endogenous pregnancy hormones, like high birth weight and jaundice in the offspring, are associated with increased risk for breast, prostate, and non-seminoma testicular cancer. Indicators of low levels, like pre-eclampsia, are associated with decreased risk. These results support the hypothesis that the pre- and perinatal periods constitute a 'time window' that is of major importance for future cancer risk. |
| Document Type: Article |
| Language: English |
| Reprint Address: Ekbom, A (reprint author), Karolinska Inst, Dept Med Epidemiol, POB 281, SE-17176 Stockholm, Sweden |
Addresses:
1. Karolinska Inst, Dept Med Epidemiol, SE-17176 Stockholm, Sweden |
| Publisher: ACADEMIC PRESS LTD, 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND |
| Subject Category: Oncology |
| IDS Number: 145KE |
| ISSN: 1044-579X |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |