| | |  | | | | Record from Web of Science® | | | | | | |
| Prospective study of nonsteroidal anti-inflammatory drugs and breast cancer |
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| Author(s): Harris RE, Kasbari S, Farrar WB |
| Source: ONCOLOGY REPORTS Volume: 6 Issue: 1 Pages: 71-73 Published: JAN-FEB 1999 |
| Times Cited: 109 References: 14 |
| Abstract: We conducted a prospective cohort study of Nonsteroidal anti-inflammatory drugs (NSAIDs) and breast cancer among 32,505 women in central Ohio, USA. After 5 years of follow-up, a total of 393 cases have been detected. The annual incidence of breast cancer per 100,00 women varied inversely with increasing intake of NSAIDs, declining from 323 among non-users to 183 among heavy users (p<0.01). Breast cancer rates decreased by about 50% with regular ibuprofen intake (p<0.01), and by about 40% with regular aspirin intake (p<0.05). The results suggest that specific NSAIDs may be effective chemopreventive agents against breast cancer. |
| Document Type: Article |
| Language: English |
| Reprint Address: Harris, RE (reprint author), Ohio State Univ, Sch Publ Hlth, Ctr Comprehens Canc, B-121 Starling Loving Hall,320 W 10th Ave, Columbus, OH 43210 USA |
Addresses:
1. Ohio State Univ, Sch Publ Hlth, Ctr Comprehens Canc, Columbus, OH 43210 USA |
| Publisher: PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS 116 35, GREECE |
| Subject Category: Oncology |
| IDS Number: 150LG |
| ISSN: 1021-335X |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |