| | |  | | | | Record from Web of Science® | | | | | | |
| Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo |
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| Author(s): Bjornson CRR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL |
| Source: SCIENCE Volume: 283 Issue: 5401 Pages: 534-537 Published: JAN 22 1999 |
| Times Cited: 910 References: 14 |
| Abstract: Stem cells are found in various organs where they participate in tissue homeostasis by replacing differentiated cells Lost to physiological turnover or injury. An investigation was performed to determine whether stem cells are restricted to produce specific cell types, namely, those from the tissue in which they reside. After transplantation into irradiated hosts; genetically labeled neural stem cells were found to produce a variety of blood cell types including myeloid and lymphoid cells as well as early hematopoietic cells. Thus, neural stem cells appear to have a wider differentiation potential than previously thought. |
| Document Type: Article |
| Language: English |
| Reprint Address: Bjornson, CRR (reprint author), Univ Washington, Dept Biochem, Seattle, WA 98195 USA |
Addresses:
1. NeuroSpheres Ltd, Calgary, AB T2N 4N1 Canada
2. CNR, Ist Mutagenesi, I-56124 Pisa, Italy
3. Ist Nazl Neurol C Besta, I-20133 Milan, Italy |
| Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 USA |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: 159YM |
| ISSN: 0036-8075 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |