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Cytokines and depression: fortuitous or causative association?
Author(s): Dantzer R, Wollman E, Vitkovic L, Yirmiya R
Source: MOLECULAR PSYCHIATRY    Volume: 4    Issue: 4    Pages: 328-332    Published: JUL 1999  
Times Cited: 73     References: 38     
Abstract: There is an increasingly impressive database concerning the possible involvement of cytokines in depression and their role in the therapeutic effects of antidepressants. Based on the discussions which took place on these issues at a recent meeting held in Roscoff, France, this perspective summarizes in a critical way the evidence in favor of such a possibility, and points out the needs for further research to clarify both the nature of the subtle dysregulations that affect neuroendocrine-immune interactions in depressive disorders and their contribution to psychopathology.
Document Type: Article
Language: English
Reprint Address: Dantzer, R (reprint author), INRA, INSERM, U394, Rue Camille St Saens, F-33077 Bordeaux, France
Addresses:
1. INRA, INSERM, U394, F-33077 Bordeaux, France
2. CNRS, Paris, France
3. CNRS, INSERM, Montpellier, France
4. Hebrew Univ Jerusalem, Dept Psychol, Mt Scopus, Israel
Publisher: STOCKTON PRESS, HOUNDMILLS, BASINGSTOKE RG21 6XS, HAMPSHIRE, ENGLAND
Subject Category: Biochemistry & Molecular Biology; Neurosciences; Psychiatry
IDS Number: 235PH
ISSN: 1359-4184
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