| | |  | | | | Record from Web of Science® | | | | | | |
| Clathrin coat construction in endocytosis |
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| Author(s): Pearse BMF, Smith CJ, Owen DJ |
| Source: CURRENT OPINION IN STRUCTURAL BIOLOGY Volume: 10 Issue: 2 Pages: 220-228 Published: APR 2000 |
| Times Cited: 54 References: 76 |
| Abstract: Electron cryomicroscopy of the clathrin coat and X-ray crystallography of parts of the clathrin heavy chain combine to give a detailed picture of the clathrin molecule, assembled as a cage. Recently determined domain structures of other components of the endocytic machinery, particularly the mu 2 subunit and the alpha-appendage domain of the AP2 adaptor complex, provide important information on the sequence of recognition events involved in the dynamic process of clathrin coat assembly. |
| Document Type: Review |
| Language: English |
| Reprint Address: Pearse, BMF (reprint author), MRC, Mol Biol Lab, Hills Rd, Cambridge CB2 2QH, England |
Addresses:
1. MRC, Mol Biol Lab, Cambridge CB2 2QH, England
2. Univ London Birkbeck Coll, Dept Crystallog, London WC1E 7HX, England |
| Publisher: CURRENT BIOLOGY LTD, 84 THEOBALDS RD, LONDON WC1X 8RR, ENGLAND |
| Subject Category: Biochemistry & Molecular Biology; Cell Biology |
| IDS Number: 306DW |
| ISSN: 0959-440X |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |