| | |  | | | | Record from Web of Science® | | | | | | |
| Lateral gene transfer and the nature of bacterial innovation |
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| Author(s): Ochman H, Lawrence JG, Groisman EA |
| Source: NATURE Volume: 405 Issue: 6784 Pages: 299-304 Published: MAY 18 2000 |
| Times Cited: 964 References: 71 |
| Abstract: Unlike eukaryotes, which evolve principally through the modification of existing genetic information, bacteria have obtained a significant proportion of their genetic diversity through the acquisition of sequences from distantly related organisms. Horizontal gene transfer produces extremely dynamic genomes in which substantial amounts of DNA are introduced into and deleted from the chromosome. These lateral transfers have effectively changed the ecological and pathogenic character of bacterial species. |
| Document Type: Review |
| Language: English |
| Reprint Address: Ochman, H (reprint author), Univ Arizona, Dept Ecol & Evolutionary Biol, Tucson, AZ 85721 USA |
Addresses:
1. Univ Arizona, Dept Ecol & Evolutionary Biol, Tucson, AZ 85721 USA
2. Univ Pittsburgh, Dept Biol Sci, Pittsburgh, PA 15260 USA
3. Washington Univ, Sch Med, Howard Hughes Med Inst, Dept Mol Microbiol, St Louis, MO 63110 USA |
| Publisher: MACMILLAN MAGAZINES LTD, PORTERS SOUTH, 4 CRINAN ST, LONDON N1 9XW, ENGLAND |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: 314YT |
| ISSN: 0028-0836 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |