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| Acute pancreatitis during immunosuppression with tacrolimus following an allogeneic umbilical cord blood transplantation |
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| Author(s): Nieto Y, Russ P, Everson G, Bearman SI, Cagnoni PJ, Jones RB, Shpall EJ |
| Source: BONE MARROW TRANSPLANTATION Volume: 26 Issue: 1 Pages: 109-111 Published: JUL 2000 |
| Times Cited: 12 References: 17 |
| Abstract: Tacrolimus is increasingly used for graft-versus-host disease (GVHD) prophylaxis and therapy in the allogeneic stem cell transplant (allo-SCT) setting. Pancreatitis, previously described as a side-effect of cyclosporine, has not been reported in allo-SCT recipients receiving tacrolimus, We present here a case of acute pancreatitis in a 28-year-old patient with chronic myelogenous leukemia (CML) who received an unrelated umbilical cord blood transplant (UCBT) and tacrolimus for GVHD prophylaxis. On day +31 post-transplant, she developed severe acute pancreatitis with multiorgan failure, from which she recovered completely. Tacrolimus was the probable cause of pancreatitis in this patient. |
| Document Type: Article |
| Language: English |
| Reprint Address: Nieto, Y (reprint author), Univ Colorado, Bone Marrow Transplant Program, B 190,4200 E 9th Ave, Denver, CO 80262 USA |
Addresses:
1. Univ Colorado, Bone Marrow Transplant Program, Denver, CO 80262 USA
2. Univ Colorado, Dept Radiol, Denver, CO 80262 USA
3. Univ Colorado, Dept Gastroenterol, Denver, CO 80262 USA |
| Publisher: NATURE PUBLISHING GROUP, HOUNDMILLS, BASINGSTOKE RG21 6XS, HAMPSHIRE, ENGLAND |
| Subject Category: Biophysics; Oncology; Hematology; Immunology; Transplantation |
| IDS Number: 334KP |
| ISSN: 0268-3369 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |