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| Vacuolar-type H+-ATPase distribution in unstimulated and acetylcholine-activated isolated human eccrine sweat glands |
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| Author(s): Bovell DL, Clunes MT, Roussa E, Burry J, Elder HY |
| Source: HISTOCHEMICAL JOURNAL Volume: 32 Issue: 7 Pages: 409-413 Published: JUL 2000 |
| Times Cited: 8 References: 36 |
| Abstract: The presence and cellular distribution of subunits of the V-1 sector of the vacuolar-type H+-ATPase (V-ATPase) was investigated in isolated human eccrine sweat glands. In every instance, V-ATPase was located in the cytoplasm and apical membranes of the luminal cells of the reabsorptive duct segment. In the secretory coil, both diffuse and perinuclear staining was demonstrated in the secretory cells, with additional expression at the apical and basolateral membranes and on the intercellular canaliculi. There was no detectable difference in V-ATPase expression as a result of prior application of 100 mu M acetylcholine. |
| Document Type: Article |
| Language: English |
| Reprint Address: Bovell, DL (reprint author), Glasgow Caledonian Univ, Sch Biol & Biomed Sci, Glasgow G4 0BA, Lanark Scotland |
Addresses:
1. Glasgow Caledonian Univ, Sch Biol & Biomed Sci, Glasgow G4 0BA, Lanark Scotland
2. Univ Saarland, Dept Anat, D-6650 Homburg, Germany
3. Univ Glasgow, Inst Biomed & Life Sci, Glasgow, Lanark Scotland |
| Publisher: KLUWER ACADEMIC PUBL, SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS |
| Subject Category: Cell Biology |
| IDS Number: 342FW |
| ISSN: 0018-2214 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |