| | |  | | | | Record from Web of Science® | | | | | | |
| Monoclonal antibody therapy for solid tumors |
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| Author(s): Green MC, Murray JL, Hortobagyi GN |
| Source: CANCER TREATMENT REVIEWS Volume: 26 Issue: 4 Pages: 269-286 Published: AUG 2000 |
| Times Cited: 74 References: 158 |
| Abstract: Monoclonal antibody therapy for solid tumors has many theoretical attractions and a long history. Until recently, with the approval and widespread use of rituximab (Rituxan) and trastuzumab (Herceptin), monoclonal antibody therapy for tumors had not had significant success. This article reviews basic theories behind antibody development and their clinical implementation as treatment for solid tumors. Medline was searched for articles over the past 15 years dealing with laboratory and clinical applications of antibody therapy for solid tumors. In addition, American Society of Clinical Oncology (ASCO) abstracts from the past 3 years were reviewed to complement the Medline search. This article focuses on treatment for common solid tumors, including breast, colon and lung cancers. (C) 2000 Harcourt Publishers Ltd. |
| Document Type: Review |
| Language: English |
| Reprint Address: Hortobagyi, GN (reprint author), Univ Texas, MD Anderson Canc Ctr, Dept Breast Med Oncol, 1515 Holcombe Blvd,Box 56, Houston, TX 77030 USA |
Addresses:
1. Univ Texas, MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USA |
| Publisher: W B SAUNDERS CO LTD, 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND |
| Subject Category: Oncology |
| IDS Number: 343WM |
| ISSN: 0305-7372 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |