| | |  | | | | Record from Web of Science® | | | | | | |
| Angiogenesis in cancer and other diseases |
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| Author(s): Carmeliet P, Jain RK |
| Source: NATURE Volume: 407 Issue: 6801 Pages: 249-257 Published: SEP 14 2000 |
| Times Cited: 2,565 References: 75 |
| Abstract: Pathological angiogenesis is a hallmark of cancer and various ischaemic and inflammatory diseases. Concentrated efforts in this area of research are leading to the discovery of a growing number of pro- and anti- angiogenic molecules, some of which are already in clinical trials. The complex interactions among these molecules and how they affect vascular structure and function in different environments are now beginning to be elucidated. This integrated understanding is leading to the development of a number of exciting and bold approaches to treat cancer and other diseases. But owing to several unanswered questions, caution is needed. |
| Document Type: Review |
| Language: English |
| Reprint Address: Carmeliet, P (reprint author), Katholieke Univ Leuven VIB, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium |
Addresses:
1. Katholieke Univ Leuven VIB, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium
2. Massachusetts Gen Hosp, Dept Radiat Oncol, Steele Lab Tumor Biol, Boston, MA 02114 USA
3. Harvard Univ, Sch Med, Boston, MA 02114 USA |
| Publisher: MACMILLAN PUBLISHERS LTD, PORTERS SOUTH, 4 CRINAN ST, LONDON N1 9XW, ENGLAND |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: 352VX |
| ISSN: 0028-0836 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |