| | |  | | | | Record from Web of Science® | | | | | | |
| Oxidants, oxidative stress and the biology of ageing |
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| Author(s): Finkel T, Holbrook NJ |
| Source: NATURE Volume: 408 Issue: 6809 Pages: 239-247 Published: NOV 9 2000 |
| Times Cited: 1,757 References: 106 |
| Abstract: Living in an oxygenated environment has required the evolution of effective cellular strategies to detect and detoxify metabolites of molecular oxygen known as reactive oxygen species. Here we review evidence that the appropriate and inappropriate production of oxidants, together with the ability of organisms to respond to oxidative stress, is intricately connected to ageing and life span. |
| Document Type: Review |
| Language: English |
| Reprint Address: Finkel, T (reprint author), NHLBI, Mol Biol Lab, NIH, Bldg 10-6N-240,10 Ctr Dr, Bethesda, MD 20892 USA |
Addresses:
1. NHLBI, Mol Biol Lab, NIH, Bethesda, MD 20892 USA
2. NIA, Biol Chem Lab, NIH, Baltimore, MD 21224 USA |
| Publisher: MACMILLAN PUBLISHERS LTD, PORTERS SOUTH, 4 CRINAN ST, LONDON N1 9XW, ENGLAND |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: 371LL |
| ISSN: 0028-0836 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |