| | |  | | | | Record from Web of Science® | | | | | | |
| Insulin/IGF signalling and ageing: seeing the bigger picture |
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| Author(s): Gems D, Partridge L |
| Source: CURRENT OPINION IN GENETICS & DEVELOPMENT Volume: 11 Issue: 3 Pages: 287-292 Published: JUN 2001 |
| Times Cited: 92 References: 54 |
| Abstract: Although the underlying mechanisms of ageing are not understood, it is known that the longevity of the nematode Caenorhabditis elegans is modulated by an insulin/IGF-signalling pathway. The focus now is on how this pathway is regulated, how it controls nematode ageing, and how this relates to the ageing process in higher animals. |
| Document Type: Review |
| Language: English |
| Reprint Address: Gems, D (reprint author), UCL, Dept Biol, 4 Stephenson Way, London NW1 2HE, England |
Addresses:
1. UCL, Dept Biol, London NW1 2HE, England |
| Publisher: CURRENT BIOLOGY LTD, 84 THEOBALDS RD, LONDON WC1X 8RR, ENGLAND |
| Subject Category: Cell Biology; Genetics & Heredity |
| IDS Number: 437TW |
| ISSN: 0959-437X |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |