| | |  | | | | Record from Web of Science® | | | | | | |
| Moving towards the next generation |
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| Author(s): Starz-Gaiano M, Lehmann R |
| Source: MECHANISMS OF DEVELOPMENT Volume: 105 Issue: 1-2 Pages: 5-18 Published: JUL 2001 |
| Times Cited: 82 References: 127 |
| Abstract: In most organisms, primordial germ cells are set aside from the cells of the body early in development. To form an embryonic gonad, germ cells often have to migrate along complex routes through and along diverse tissues until they reach the somatic part of the gonad. Recent advances have been made in the genetic analysis of these early stages of germ line development. Here we review findings from Drosophila, zebrafish, and mouse; each organism provides unique insight into the mechanisms that determine germ cell fate and the cues that may guide their migration. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved. |
| Document Type: Review |
| Language: English |
| Reprint Address: Lehmann, R (reprint author), Howard Hughes Med Inst, Skirball Inst Biomol Med, Dev Genet Program, 540 1st Ave, New York, NY 10016 USA |
Addresses:
1. Howard Hughes Med Inst, Skirball Inst Biomol Med, Dev Genet Program, New York, NY 10016 USA
2. NYU, Sch Med, New York, NY 10016 USA |
| Publisher: ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS |
| Subject Category: Developmental Biology |
| IDS Number: 456KR |
| ISSN: 0925-4773 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |