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| Allogeneic stem cell transplantation for Evans syndrome |
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| Author(s): Oyama Y, Papadopoulos EB, Miranda M, Traynor AE, Burt RK |
| Source: BONE MARROW TRANSPLANTATION Volume: 28 Issue: 9 Pages: 903-905 Published: NOV 2001 |
| Times Cited: 30 References: 21 |
| Abstract: Evans syndrome is a rare disorder characterized by combined autoimmune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA). Standard treatments consist of transfusions, corticosteroids, splenectomy, IVIG, anabolic steroids, vincristine, alkylating agents, or cyclosporine. In a patient with refractory disease, an allogeneic hematopoietic stem cell transplant (HSCT) resulted in complete clinical and serologic remission for more than 30 months. Allogeneic HSCT may be the only current curative therapy for Evans syndrome but may also be complicated by significant toxicities. |
| Document Type: Article |
| Language: English |
| Reprint Address: Burt, RK (reprint author), Northwestern Univ, Med Ctr, Div Immune Therapy & Autoimmune Dis, Chicago, IL 60611 USA |
Addresses:
1. Northwestern Univ, Med Ctr, Div Immune Therapy & Autoimmune Dis, Chicago, IL 60611 USA 2. Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA |
| Publisher: NATURE PUBLISHING GROUP, HOUNDMILLS, BASINGSTOKE RG21 6XS, HAMPSHIRE, ENGLAND |
| Subject Category: Biophysics; Oncology; Hematology; Immunology; Transplantation |
| IDS Number: 498EH |
| ISSN: 0268-3369 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |