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| Minimum information about a microarray experiment (MIAME) - toward standards for microarray data |
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| Author(s): Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, Stoeckert C, Aach J, Ansorge W, Ball CA, Causton HC, Gaasterland T, Glenisson P, Holstege FCP, Kim IF, Markowitz V, Matese JC, Parkinson H, Robinson A, Sarkans U, Schulze-Kremer S, Stewart J, Taylor R, Vilo J, Vingron M |
| Source: NATURE GENETICS Volume: 29 Issue: 4 Pages: 365-371 Published: DEC 2001 |
| Times Cited: 1,429 References: 12 |
| Abstract: Microarray analysis has become a widely used tool for the generation of gene expression data on a genomic scale. Although many significant results have been derived from microarray studies, one limitation has been the lack of standards for presenting and exchanging such data. Here we present a proposal, the Minimum Information About a Microarray Experiment (MIAME), that describes the minimum information required to ensure that microarray data can be easily interpreted and that results derived from its analysis can be independently verified. The ultimate goal of this work is to establish a standard for recording and reporting microarray-based gene expression data, which will in turn facilitate the establishment of databases and public repositories and enable the development of data analysis tools. With respect to MIAME, we concentrate on defining the content and structure of the necessary information rather than the technical format for capturing it. |
| Document Type: Editorial Material |
| Language: English |
| Reprint Address: Brazma, A (reprint author), European Bioinformat Inst, EMBL Outstn, Wellcome Trust Genome Campus, Cambridge CB10 1SD, England |
Addresses:
1. European Bioinformat Inst, EMBL Outstn, Cambridge CB10 1SD, England
2. Univ Mediterranee, Ctr Immunol Marseille Luminy, CIML, TAGC, Marseille, France
3. Inst Genome Res, TIGR, Rockville, MD USA
4. Stanford Univ, Palo Alto, CA 94304 USA
5. Univ Calif Berkeley, Berkeley, CA 94720 USA
6. Univ Penn, Philadelphia, PA 19104 USA
7. Harvard Univ, Sch Med, Dept Genet, Cambridge, MA 02138 USA
8. European Mol Biol Lab, Heidelberg, Germany
9. Imperial Coll Sch Med Microarray Ctr, CSC, London, England
10. Rockefeller Univ, New York, NY 10021 USA
11. Katholieke Univ Leuven, Louvain, Belgium
12. Univ Utrecht, Med Ctr, Utrecht, Netherlands
13. GeneLogic Inc, Gaithersburg, MD USA
14. German Genome Resource Ctr, RZDP, Berlin, Germany
15. Open Informat, Albuquerque, NM USA
16. Univ Colorado, Sch Med, Ctr Computat Pharmacol, Denver, CO USA
17. Max Planck Inst Mol Genet, Berlin, Germany |
| Publisher: NATURE AMERICA INC, 345 PARK AVE SOUTH, NEW YORK, NY 10010-1707 USA |
| Subject Category: Genetics & Heredity |
| IDS Number: 498JZ |
| ISSN: 1061-4036 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |