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| Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An international consensus |
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| Author(s): Ascioglu S, Rex JH, de Pauw B, Bennett JE, Bille J, Crokaert F, Denning DW, Donnelly JP, Edwards JE, Erjavec Z, Fiere D, Lortholary O, Maertens J, Meis JF, Patterson TF, Ritter J, Selleslag D, Shah PM, Stevens DA, Walsh TJ |
| Source: CLINICAL INFECTIOUS DISEASES Volume: 34 Issue: 1 Pages: 7-14 Published: JAN 1 2002 |
| Times Cited: 1,039 References: 35 |
| Abstract: During the past several decades, there has been a steady increase in the frequency of opportunistic invasive fungal infections (IFIs) in immunocompromised patients. However, there is substantial controversy concerning optimal diagnostic criteria for these IFIs. Therefore, members of the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group formed a consensus committee to develop standard definitions for IFIs for clinical research. On the basis of a review of literature and an international consensus, a set of research-oriented definitions for the IFIs most often seen and studied in immunocompromised patients with cancer is proposed. Three levels of probability are proposed: "proven," "probable," and "possible." The definitions are intended for use in the context of clinical and/or epidemiological research, not for clinical decision making. |
| Document Type: Article |
| Language: English |
| Reprint Address: Walsh, TJ (reprint author), NCI, 9000 Rockville Pike,Bldg 10,Rm 13N240, Bethesda, MD 20892 USA |
Addresses:
1. European Org Res Treatment Canc, Invas Infect Cooperat Grp, Brussels, Belgium
2. NIAID, Mycoses Study Grp, NIH, Bethesda, MD 20892 USA |
| Publisher: UNIV CHICAGO PRESS, 1427 E 60TH ST, CHICAGO, IL 60637-2954 USA |
| Subject Category: Immunology; Infectious Diseases; Microbiology |
| IDS Number: 498ZM |
| ISSN: 1058-4838 |
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