| Combinatorial control of gene expression by nuclear receptors and coregulators |
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| Author(s): McKenna NJ, O'Malley BW |
| Source: CELL Volume: 108 Issue: 4 Pages: 465-474 Published: FEB 22 2002 |
| Times Cited: 690 References: 102 |
| Abstract: The nuclear receptor (NR) superfamily of transcription factors regulates gene expression in response to endocrine signaling, and recruitment of coregulators affords these receptors considerable functional flexibility. We will place historical aspects of NR research in context with current opinions on their mechanism of signal transduction, and we will speculate upon future trends in the field. |
| Document Type: Review |
| Language: English |
| Reprint Address: O'Malley, BW (reprint author), Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA |
Addresses:
1. Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA |
| Publisher: CELL PRESS, 1100 MASSACHUSETTS AVE,, CAMBRIDGE, MA 02138 USA |
| Subject Category: Biochemistry & Molecular Biology; Cell Biology |
| IDS Number: 524XW |
| ISSN: 0092-8674 |