| | |  | | | | Record from Web of Science® | | | | | | |
| Extending life: Scientific prospects and political obstacles |
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| Author(s): Miller RA |
| Source: MILBANK QUARTERLY Volume: 80 Issue: 1 Pages: 155-+ Published: 2002 |
| Times Cited: 39 References: 30 |
| Abstract: Aging can be slowed in laboratory rodents by low-calorie diets, and changes in single genes can extend mouse life span by 40 percent or more. Therefore, despite its surface complexity and effects on multiple cells and intercellular systems, aging in mammals might also be retarded by both genetic and nongenetic means. If human aging could be slowed pharmacologically to the extent now possible in rodents, the effect on healthy life expectancy would exceed that of abolishing cancer, cardiovascular disease, and adult-onset diabetes. Why, then, is research on the biological control of aging and longevity poorly funded and shunned by both most scientists and those setting national research priorities? Economic disincentives, disease-specific lobby groups, scientific careerism, and ineffective nostrums, together with gerontologiphobia, must be overcome before such research can improve public health. |
| Document Type: Article |
| Language: English |
| Reprint Address: Miller, RA (reprint author), Univ Michigan, 5316 CCGCB,Box 0940, Ann Arbor, MI 48109 USA |
Addresses:
1. Univ Michigan, Ann Arbor, MI 48109 USA |
| Publisher: BLACKWELL PUBLISHERS, 350 MAIN STREET, STE 6, MALDEN, MA 02148 USA |
| Subject Category: Health Care Sciences & Services; Health Policy & Services |
| IDS Number: 534EU |
| ISSN: 0887-378X |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |