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| An expanding universe of noncoding RNAs |
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| Author(s): Storz G |
| Source: SCIENCE Volume: 296 Issue: 5571 Pages: 1260-1263 Published: MAY 17 2002 |
| Times Cited: 245 References: 48 |
| Abstract: Noncoding RNAs (ncRNAs) have been found to have roles in a great variety of processes, including transcriptional regulation, chromosome replication, RNA processing and modification, messenger RNA stability and translation, and even protein degradation and translocation. Recent studies indicate that ncRNAs are far more abundant and important than initially imagined. These findings raise several fundamental questions: How many ncRNAs are encoded by a genome? Given the absence of a diagnostic open reading frame, how can these genes be identified? How can all the functions of ncRNAs be elucidated? |
| Document Type: Editorial Material |
| Language: English |
| Reprint Address: Storz, G (reprint author), NICHHD, Cell Biol & Metab Branch, NIH, Bethesda, MD 20892 USA |
Addresses:
1. NICHHD, Cell Biol & Metab Branch, NIH, Bethesda, MD 20892 USA |
| Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 USA |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: 554BL |
| ISSN: 0036-8075 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |