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| Atopiform dermatitis |
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| Author(s): Bos JD |
| Source: BRITISH JOURNAL OF DERMATOLOGY Volume: 147 Issue: 3 Pages: 426-429 Published: SEP 2002 |
| Times Cited: 21 References: 12 |
| Abstract: It is proposed to introduce the term 'atopiform dermatitis' to describe patients who have dermatitis with many of the characteristics of true atopic dermatitis, but who are not atopic. Atopy should be defined as the genetically determined and environmentally influenced syndrome in which the primary immunological abnormality is the production of allergen-specific IgE. It is suggested that by making a distinction between atopiform dermatitis and true atopic dermatitis, subsequent genetic, immunological and therapeutic studies will be improved. Furthermore, atopiform dermatitis would be a more appropriate diagnosis for the atopic dermatitis-like skin diseases that may occur in syndromes such as phenylketonuria, Schwachman's syndrome, Wiskott-Aldrich syndrome, Netherton's syndrome, Job's syndrome, selective IgA deficiency, agammaglobulinaemia and ataxia telangiectasia. In contrast to patients with true atopy, patients with atopiform dermatitis can logically be advised that allergen avoidance is not required, as they have no allergen-specific IgE. |
| Document Type: Editorial Material |
| Language: English |
| Reprint Address: Bos, JD (reprint author), Univ Amsterdam, Acad Med Ctr, Dept Dermatol A0 235, POB 22700, NL-1100 DE Amsterdam, Netherlands |
Addresses:
1. Univ Amsterdam, Acad Med Ctr, Dept Dermatol A0 235, NL-1100 DE Amsterdam, Netherlands |
| Publisher: BLACKWELL PUBLISHING LTD, 9600 GARSINGTON RD, OXFORD OX4 2DG, OXON, ENGLAND |
| Subject Category: Dermatology |
| IDS Number: 589YR |
| ISSN: 0007-0963 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |