| | |  | | | | Record from Web of Science® | | | | | | |
| Molecular mechanisms of selector gene function and evolution |
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| Author(s): Mann RS, Carroll SB |
| Source: CURRENT OPINION IN GENETICS & DEVELOPMENT Volume: 12 Issue: 5 Pages: 592-600 Published: OCT 2002 |
| Times Cited: 69 References: 63 |
| Abstract: Selector proteins regulate the formation and identity of animal body regions, organs, tissues, and cell types. Recent studies have focused on the regulation of the DNA binding and transcriptional regulatory activity of this special class of transcription factors. Elucidation of the architecture of selector-regulated target gene enhancers and gene networks, and comparative studies of selector protein function are providing important insights into the evolution of development and morphology. |
| Document Type: Review |
| Language: English |
| Reprint Address: Mann, RS (reprint author), Columbia Univ, Dept Biochem & Mol Biophys, 630 W 168th St, New York, NY 10032 USA |
Addresses:
1. Columbia Univ, Dept Biochem & Mol Biophys, New York, NY 10032 USA
2. Univ Wisconsin, Howard Hughes Med Inst, Madison, WI 53706 USA
3. Univ Wisconsin, Mol Biol Lab, Madison, WI 53706 USA |
| Publisher: CURRENT BIOLOGY LTD, 84 THEOBALDS RD, LONDON WC1X 8RR, ENGLAND |
| Subject Category: Cell Biology; Genetics & Heredity |
| IDS Number: 591UG |
| ISSN: 0959-437X |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |