| | |  | | | | Record from Web of Science® | | | | | | |
| Gene expression during the life cycle of Drosophila melanogaster |
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| Author(s): Arbeitman MN, Furlong EEM, Imam F, Johnson E, Null BH, Baker BS, Krasnow MA, Scott MP, Davis RW, White KP |
| Source: SCIENCE Volume: 297 Issue: 5590 Pages: 2270-2275 Published: SEP 27 2002 |
| Times Cited: 359 References: 28 |
| Abstract: Molecular genetic studies of Drosophila melanogaster have led to profound advances in understanding the regulation of development. Here we report gene expression patterns for nearly one-third of all Drosophila genes during a complete time course of development. Mutations that eliminate eye or germline tissue were used to further analyze tissue-specific gene expression programs. These studies de ne major characteristics of the transcriptional programs that underlie the life cycle, compare development in males and females, and show that large-scale gene expression data collected from whole animals can be used to identify genes expressed in particular tissues and organs or genes involved in specific biological and biochemical processes. |
| Document Type: Article |
| Language: English |
| Reprint Address: White, KP (reprint author), Stanford Univ, Genome Technol Ctr, 855 Calif Ave, Palo Alto, CA 94306 USA |
Addresses:
1. Stanford Univ, Genome Technol Ctr, Palo Alto, CA 94306 USA
2. Yale Univ, Sch Med, Dept Genet, New Haven, CT 06520 USA
3. Stanford Univ, Dept Biol Sci, Stanford, CA 94305 USA
4. Stanford Univ, Dept Dev Biol, Stanford, CA 94305 USA
5. Stanford Univ, Dept Genet, Stanford, CA 94305 USA
6. Stanford Univ, Dept Biochem, Stanford, CA 94305 USA
7. Stanford Univ, Howard Hughes Med Inst, Stanford, CA 94305 USA
8. European Mol Biol Lab, Dev Biol Program, D-69117 Heidelberg, Germany
9. Univ Oregon, Inst Mol Biol, Eugene, OR 97403 USA |
| Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 USA |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: 597LA |
| ISSN: 0036-8075 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |