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Nogo on the go
Author(s): McKerracher L, Winton MJ
Source: NEURON    Volume: 36    Issue: 3    Pages: 345-348    Published: OCT 24 2002  
Times Cited: 62     References: 20     
Abstract: Growth inhibition in the central nervous system (CNS) is a major barrier to axon regeneration. Recent findings indicate that three distinct myelin proteins, myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte-myelin glycoprotein (OMgp), inhibit axon growth by binding a common receptor, the Nogo66 receptor (NgR), and likely converge on a common signaling cascade.
Document Type: Review
Language: English
Reprint Address: McKerracher, L (reprint author), Univ Montreal, Dept Pathol & Biol Cellulaire, 2900 Edouard Montpetit, Montreal, PQ H3T 1J4 Canada
Addresses:
1. Univ Montreal, Dept Pathol & Biol Cellulaire, Montreal, PQ H3T 1J4 Canada
Publisher: CELL PRESS, 1100 MASSACHUSETTS AVE, CAMBRIDGE, MA 02138 USA
Subject Category: Neurosciences
IDS Number: 608ZE
ISSN: 0896-6273
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