| | |  | | | | Record from Web of Science® | | | | | | |
| Preimplantation genetic diagnosis |
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| Author(s): Braude P, Pickering S, Flinter F, Ogilvie CM |
| Source: NATURE REVIEWS GENETICS Volume: 3 Issue: 12 Pages: 941-953 Published: DEC 2002 |
| Times Cited: 71 References: 113 |
| Abstract: Preimplantation genetic diagnosis (PGD) is an evolving technique that provides a practical alternative to prenatal diagnosis and termination of pregnancy for couples who are at substantial risk of transmitting a serious genetic disorder to their offspring. Samples for genetic testing are obtained from oocytes or cleaving embryos after in vitro fertilization. Only embryos that are shown to be free of the genetic disorders are made available for replacement in the uterus, in the hope of establishing a pregnancy. PGD has provided unique insights into aspects of reproductive genetics and early human development, but has also raised important new ethical issues about assisted human reproduction. |
| Document Type: Review |
| Language: English |
| Reprint Address: Braude, P (reprint author), Guys Hosp, Ctr Preimplantat Genet Diag, Thomas Guy House, London SE1 9RT, England |
Addresses:
1. Guys Hosp, Ctr Preimplantat Genet Diag, London SE1 9RT, England |
| Publisher: NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND |
| Subject Category: Genetics & Heredity |
| IDS Number: 621CU |
| ISSN: 1471-0056 |
| DOI: 10.1038/nrg953 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |