| | |  | | | | Record from Web of Science® | | | | | | |
| Pattern recognition receptors: Doubling up for the innate immune response |
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| Author(s): Gordon S |
| Source: CELL Volume: 111 Issue: 7 Pages: 927-930 Published: DEC 27 2002 |
| Times Cited: 385 References: 13 |
| Abstract: Antigen presenting cells (macrophages and dendritic cells) express pattern recognition molecules that are thought to recognize foreign ligands during early phases of the immune response. The best known of these are probably the Toll-like receptors, but a number of other receptors are also involved. Several of these recognize endogenous as well as exogenous ligands, suggesting that they play a dual role in normal tissue function and host defense. |
| Document Type: Review |
| Language: English |
| Reprint Address: Gordon, S (reprint author), Univ Oxford, Sir William Dunn Sch Pathol, S Parks Rd, Oxford OX1 3RE, England |
Addresses:
1. Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England |
| Publisher: CELL PRESS, 1100 MASSACHUSETTS AVE,, CAMBRIDGE, MA 02138 USA |
| Subject Category: Biochemistry & Molecular Biology; Cell Biology |
| IDS Number: 630AU |
| ISSN: 0092-8674 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |