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| Dual role of TOC1 in the control of circadian and photomorphogenic responses in Arabidopsis |
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| Author(s): Mas P, Alabadi D, Yanovsky MJ, Oyama T, Kay SA |
| Source: PLANT CELL Volume: 15 Issue: 1 Pages: 223-236 Published: JAN 2003 |
| Times Cited: 112 References: 48 |
| Abstract: To examine the role of the TOC1 (TIMING OF CAB EXPRESSION1) gene in the Arabidopsis circadian system, we generated a series of transgenic plants expressing a gradation in TOC1 levels. Silencing of the TOC1 gene causes arrhythmia in constant darkness and in various intensities of red light, whereas in blue light, the clock runs faster in silenced plants than in wild-type plants. Increments in TOCI gene dosage delayed the pace of the clock, whereas TOC1 overexpression abolished rhythmicity in all light conditions tested. Our results show that TOC1 RNA interference and toc1-2 mutant plants displayed an important reduction in sensitivity to red and far-red light in the control of hypocotyl elongation, whereas increments in TOC1 gene dosage clearly enhanced light sensitivity. Furthermore, the red light-mediated induction of CCA1/LHY expression was decreased in TOCI RNA interference and toc1-2 mutant plants, indicating a role for TOC1 in the phytochrome regulation of circadian gene expression. We conclude that TOC1 is an important component of the circadian clock in Arabidopsis with a crucial function in the integration of light signals to control circadian and morphogenic responses. |
| Document Type: Article |
| Language: English |
| Reprint Address: Kay, SA (reprint author), Scripps Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA |
Addresses:
1. Scripps Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA
2. Scripps Res Inst, Inst Childhood & Neglected Dis, La Jolla, CA 92037 USA |
| Publisher: AMER SOC PLANT BIOLOGISTS, 15501 MONONA DRIVE, ROCKVILLE, MD 20855 USA |
| Subject Category: Biochemistry & Molecular Biology; Plant Sciences; Cell Biology |
| IDS Number: 637KQ |
| ISSN: 1040-4651 |
| DOI: 10.1105/tpc.006734 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |