| | |  | | | | Record from Web of Science® | | | | | | |
| Genetics and pathophysiology of human obesity |
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| Author(s): Cummings DE, Schwartz MW |
| Source: ANNUAL REVIEW OF MEDICINE-SELECTED TOPICS IN THE CLINICAL SCIENCES Volume: 54 Pages: 453-471 Published: 2003 |
| Times Cited: 134 References: 110 |
| Abstract: Obesity has become a leading public health concern. Over 1 billion people are now overweight or obese, and the prevalence of these conditions is rising rapidly. Remarkable new insights into the mechanisms that control body weight are providing an increasingly detailed framework for a better understanding of obesity pathogenesis. Key peripheral signals, such as leptin, insulin, and ghrelin, have been linked to hypothalamic neuropeptide systems, and the anatomic and functional networks that integrate these systems have begun to be elucidated. This article highlights some of these recent findings and their implications for the future of obesity treatment. |
| Document Type: Review |
| Language: English |
| Reprint Address: Cummings, DE (reprint author), Univ Washington, VA Puget Sound Hlth Care Syst, Dept Med, Div Metab Endocrinol & Nutr, Seattle, WA 98195 USA |
Addresses:
1. Univ Washington, VA Puget Sound Hlth Care Syst, Dept Med, Div Metab Endocrinol & Nutr, Seattle, WA 98195 USA
2. Harborview Med Ctr, Seattle, WA 98195 USA |
| Publisher: ANNUAL REVIEWS, 4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0139 USA |
| Subject Category: Medicine, General & Internal |
| IDS Number: 670WV |
| ISSN: 0066-4219 |
| DOI: 10.1146/annurev.med.54.101601.152403 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |