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Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS)
Author(s): Seto WH, Tsang D, Yung RWH, Ching TY, Ng TK, Ho M, Ho LM, Peiris JSM
Source: LANCET    Volume: 361    Issue: 9368    Pages: 1519-1520    Published: MAY 3 2003  
Times Cited: 236     References: 5     
Abstract: We did a case-control study in five Hong Kong hospitals, with 241 non-infected and 13 infected staff with documented exposures to 31 index patients with severe acute respiratory syndrome (SARS) during patient care. All participants were surveyed about use of mask, gloves, gowns, and hand-washing, as recommended under droplets and contact precautions when caring for index patients with SARS. 69 staff who reported use of all four measures were not infected, whereas all Infected staff had omitted at least one measure (p=0.0224). Fewer staff who wore masks (p=0.0001), gowns (p=0.006), and washed their hands (p=0.047) became infected compared with those who didn't, but stepwise logistic regression was significant only for masks (p=0.011). Practice of droplets precaution and contact precaution is adequate in significantly reducing the risk of infection after exposures to patients with SARS. The protective role of the mask suggests that in hospitals, infection is transmitted by droplets.
Document Type: Article
Language: English
Reprint Address: Seto, WH (reprint author), Queen Mary Hosp, Dept Microbiol, Pokfulam Rd, Hong Kong, Hong Kong Peoples R China
Addresses:
1. Queen Mary Hosp, Dept Microbiol, Hong Kong, Hong Kong Peoples R China
2. Queen Elizabeth Hosp, Dept Microbiol, Hong Kong, Hong Kong Peoples R China
3. Pamela Nethersole Youde Hosp, Dept Microbiol, Hong Kong, Hong Kong Peoples R China
4. Princess Margaret Hosp, Dept Microbiol, Hong Kong, Hong Kong Peoples R China
5. Kwong Wah Hosp, Dept Microbiol, Hong Kong, Hong Kong Peoples R China
6. Univ Hong Kong, Dept Community Med, Hong Kong, Hong Kong Peoples R China
7. Univ Hong Kong, Dept Microbiol, Hong Kong, Hong Kong Peoples R China
Publisher: LANCET LTD, 84 THEOBALDS RD, LONDON WC1X 8RR, ENGLAND
Subject Category: Medicine, General & Internal
IDS Number: 674WB
ISSN: 0140-6736
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