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Self-measured versus ambulatory blood pressure in the diagnosis of hypertension
Author(s): Hond ED, Celis H, Fagard R, Keary L, Leeman M, O'Brien E, Vandenhoven G, Staessen JA
Source: JOURNAL OF HYPERTENSION    Volume: 21    Issue: 4    Pages: 717-722    Published: APR 2003  
Times Cited: 31     References: 19     
Abstract: Objective We examined to what extent self-measurement of blood pressure at home (HBP) can be an alternative to ambulatory monitoring (ABP) to diagnose white-coat hypertension.

Methods In 247 untreated patients, we compared the white-coat effects obtained by HBP and ABP. The thresholds to diagnose hypertension were greater than or equal to140/greater than or equal to90 mmHg for conventional blood pressure (CBP) and greater than or equal to135/greater than or equal to85 mmHg for daytime ABP and HBP.

Results Mean systolic/diastolic CBP, HBP and AB P were 155.4/100.0,143.1/91.5 and 148.1/95.0 mmHg, respectively. The white-coat effect was 5.0/3.5 mmHg larger on HBP compared with ABP (112.3/8.6 versus 7.2/5.0 mmHg; P < 0.001). The correlation coefficients between the white-coat effects based on HBP and ABP were 0.74 systolic and 0.60 diastolic (P < 0.001). With ABP as a reference, the specificity of HBP to detect white-coat hypertension was 88.6%, and the sensitivity was 68.4%.

Conclusion Our findings are in line with the recommendations of the ASH Ad Hoc Panel that recommends HBP for screening while ABP has a better prognostic accuracy.

Document Type: Article
Language: English
Reprint Address: Hond, ED (reprint author), Katholieke Univ Leuven, Dept Mol & Cardiovasc Res, Hypertens & Cardiovasc Rehabil Unit, Study Coordinating Ctr,Lab Hypertensie Gebouw Ond, Herestr 49, B-3000 Louvain, Belgium
Addresses:
1. Katholieke Univ Leuven, Dept Mol & Cardiovasc Res, Hypertens & Cardiovasc Rehabil Unit, Study Coordinating Ctr,Lab Hypertensie Gebouw Ond, B-3000 Louvain, Belgium
2. AstraZeneca NV SA, Brussels, Belgium
3. Beaumont Hosp, Blood Pressure Unit, Dublin 9, Ireland
4. Beaumont Hosp, ADAPT Ctr, Dublin 9, Ireland
5. Free Univ Brussels, Erasme Univ Hosp, Hypertens Unit, Brussels, Belgium
Publisher: LIPPINCOTT WILLIAMS & WILKINS, 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
Subject Category: Peripheral Vascular Disease
IDS Number: 676KK
ISSN: 0263-6352
DOI: 10.1097/01.hjh.0000052488.18130.0a
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