| | |  | | | | Record from Web of Science® | | | | | | |
| Integrin signaling to the actin cytoskeleton |
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| Author(s): DeMali KA, Wennerberg K, Burridge K |
| Source: CURRENT OPINION IN CELL BIOLOGY Volume: 15 Issue: 5 Pages: 572-582 Published: OCT 2003 |
| Times Cited: 199 References: 102 |
| Abstract: Integrin engagement stimulates the activity of numerous signaling molecules, including the Rho family of GTPases, tyrosine phosphatases, cAMP-dependent protein kinase and protein kinase C, and stimulates production of PtdIns(4,5)P-2. Integrins promote actin assembly via the recruitment of molecules that directly activate the actin polymerization machinery or physically link it to sites of cell adhesion. |
| Document Type: Review |
| Language: English |
| Reprint Address: DeMali, KA (reprint author), Univ N Carolina, Dept Cell & Dev Biol, Chapel Hill, NC 27599 USA |
Addresses:
1. Univ N Carolina, Dept Cell & Dev Biol, Chapel Hill, NC 27599 USA
2. Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA |
| Publisher: CURRENT BIOLOGY LTD, 84 THEOBALDS RD, LONDON WC1X 8RR, ENGLAND |
| Subject Category: Cell Biology |
| IDS Number: 730TP |
| ISSN: 0955-0674 |
| DOI: 10.1016/S0955-0674(03)00109-1 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |