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| microRNAs: Runts of the genome assert themselves |
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| Author(s): Lai EC |
| Source: CURRENT BIOLOGY Volume: 13 Issue: 23 Pages: R925-R936 Published: DEC 2 2003 |
| Times Cited: 81 References: 94 |
| Abstract: microRNAs form an abundant class of 21-22 nucleotide, non-coding RNA that is common to diverse species of multicellular life. Although they are currently the subject of intense, directed study, the path toward their discovery has been dominated by chance and serendipity. In this review, I examine how these tiny molecules have risen from genetic obscurity to scientific stardom, and discuss the emerging biological functions of these novel riboregulators. |
| Document Type: Review |
| Language: English |
| Reprint Address: Lai, EC (reprint author), Univ Calif Berkeley, Howard Hughes Med Inst, Dept Mol & Cell Biol, 545 Life Sci Addit, Berkeley, CA 94720 USA |
Addresses:
1. Univ Calif Berkeley, Howard Hughes Med Inst, Dept Mol & Cell Biol, Berkeley, CA 94720 USA |
| Publisher: CELL PRESS, 1100 MASSACHUSETTS AVE, CAMBRIDGE, MA 02138 USA |
| Subject Category: Biochemistry & Molecular Biology |
| IDS Number: 750NG |
| ISSN: 0960-9822 |
| DOI: 10.1016/j.cub.2003.11.017 |
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