| | |  | | | | Record from Web of Science® | | | | | | |
| Synthesis of vitamin D in skin after burns |
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| Author(s): Klein GL, Chen TC, Holick MF, Langman CB, Price H, Celis MM, Herndon DN |
| Source: LANCET Volume: 363 Issue: 9405 Pages: 291-292 Published: JAN 24 2004 |
| Times Cited: 6 References: 5 |
| Abstract: Severe burn injury is associated with vitamin D deficiency, low bone turnover, and abnormalities in calcium homoeostasis. Patients do not routinely receive vitamin D supplementation and sun exposure is currently not controlled. By analysis of skin biopsy samples for vitamin D3 precursors after exposure to ultraviolet B light we found that the conversion of 7-dehydrocholesterol to previtamin D3 was reduced in children a mean of 14 months after the burn. Low serum 25-hydroxyvitamin D concentrations were also found. We conclude that vitamin D supplementation is necessary after burn injury. |
| Document Type: Article |
| Language: English |
| Reprint Address: Klein, GL (reprint author), Univ Texas, Med Branch, Childrens Hosp, 301 Univ Blvd, Galveston, TX 77555 USA |
Addresses:
1. Univ Texas, Med Branch, Dept Paediat, Galveston, TX 77550 USA
2. Univ Texas, Med Branch, Dept Surg, Galveston, TX 77550 USA
3. Shriners Burns Hosp, Galveston, TX USA
4. Boston Univ, Med Ctr, Dept Med, Boston, MA USA
5. Northwestern Univ, Childrens Mem Hosp, Feinberg Sch Med, Chicago, IL 60614 USA |
| Publisher: LANCET LTD, 84 THEOBALDS RD, LONDON WC1X 8RR, ENGLAND |
| Subject Category: Medicine, General & Internal |
| IDS Number: 766FQ |
| ISSN: 0140-6736 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |