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Diagnosis and treatment of cholangiocarcinoma
Author(s): Anderson CD, Pinson CW, Berlin J, Chari RS
Source: ONCOLOGIST    Volume: 9    Issue: 1    Pages: 43-57    Published: 2004  
Times Cited: 39     References: 131     
Abstract: Cholangiocarcinoma presents a formidable diagnostic and treatment challenge. The majority of patients present with unresectable disease and have a survival of less than 12 months following diagnosis. Progress has been made by the appropriate selection of patients for treatment options including resection, with the routine use of more aggressive resections in order to achieve margin-negative resections. This has resulted in longer survival times for these patients. Neoadjuvant and adjuvant therapies have, for the most part, not improved survival in patients with this tumor, and new strategies are needed to improve this line of therapy. The prognosis for unresectable patients is poor, and palliative measures should be aimed at increasing quality of life first and increasing survival second.
Document Type: Review
Language: English
Reprint Address: Chari, RS (reprint author), Vanderbilt Univ, Med Ctr, Div Hepatobiliary Surg & Liver Transplantat, Dept Surg, Suite 801 Oxford House,1313 21st Ave S, Nashville, TN 37232 USA
Addresses:
1. Vanderbilt Univ, Med Ctr, Div Hepatobiliary Surg & Liver Transplantat, Dept Surg, Nashville, TN 37232 USA
2. Vanderbilt Univ, Med Ctr, Dept Oncol, Nashville, TN 37232 USA
3. Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Dept Canc Biol, Nashville, TN 37232 USA
Publisher: ALPHAMED PRESS, ONE PRESTIGE PLACE, STE 290, MIAMISBURG, OH 45342-3758 USA
Subject Category: Oncology
IDS Number: 767ZK
ISSN: 1083-7159
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