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| Pathologic assessment of vasculopathies in pulmonary hypertension |
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| Author(s): Pietra GG, Capron F, Stewart S, Leone O, Humbert M, Robbins IM, Reid LM, Tuder RM |
| Source: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Volume: 43 Issue: 12 Pages: 25S-32S Supplement: Suppl. S Published: JUN 16 2004 |
| Times Cited: 71 References: 33 |
| Abstract: Pulmonary arterial hypertension (PAH) includes various forms of pulmonary hypertension of different etiology but similar clinical presentation and functional derangement. Histopathological vascular changes in all forms of PAH are qualitatively similar but with quantitative differences in the distribution and prevalence of pathological changes in various portions of the pulmonary vascular bed. The documentation of these topographic variations in the response of the pulmonary vasculature to injury may be important to understand the pathogenesis of the various subsets of PAR To standardize the precise histopathological documentation of the pulmonary vasculopathy in PAH we propose a histopathological classification that includes both the predominant segment of the pulmonary vasculature affected and the possible coexistence of pathological changes in other vascular segments. (C) 2004 by the American College of Cardiology Foundation. |
| Document Type: Proceedings Paper |
| Language: English |
| Reprint Address: Pietra, GG (reprint author), , Via San Giorgio 23, CH-6976 Castagnola, Switzerland |
Addresses:
1. Univ Penn, Sch Med, Dept Pathol, Philadelphia, PA 19104 USA
2. Hop Pitie, Serv Anat Pathol, F-75651 Paris 13, France
3. Papworth Hosp, Cambridge CB3 8RE, England
4. Azienda Osped S Orsola Malpighi Bologna, Dept Pathol, Bologna, Italy
5. Univ Paris Sud, Hop Paris, Hop Antoine Beclere, Serv Pneumol & Reanimat Resp, Clamart, France
6. Vanderbilt Univ, Med Ctr, Adult Pulm Hypertens Ctr, Nashville, TN USA
7. Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
8. Johns Hopkins Univ, Sch Med, Div Cardiopulm Pathol, Baltimore, MD USA |
| Publisher: ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA |
| Subject Category: Cardiac & Cardiovascular Systems |
| IDS Number: 831QI |
| ISSN: 0735-1097 |
| DOI: 10.1016/j.jacc.2004.02.033 |
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