| | |  | | | | Record from Web of Science® | | | | | | |
| Lack of a fusion requirement for development of bone marrow-derived epithelia |
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| Author(s): Harris RG, Herzog EL, Bruscia EM, Grove JE, Van Arnam JS, Krause DS |
| Source: SCIENCE Volume: 305 Issue: 5680 Pages: 90-93 Published: JUL 2 2004 |
| Times Cited: 216 References: 23 |
| Abstract: Analysis of developmental plasticity of bone marrow - derived cells (BMDCs) is complicated by the possibility of cell-cell fusion. Here we demonstrate that epithelial cells can develop from BMDCs without cell-cell fusion. We use the Cre/lox system together with beta-galactosidase and enhanced green fluorescent protein expression in transgenic mice to identify epithelial cells in the lung, liver, and skin that develop from BMDCs without cell fusion. |
| Document Type: Article |
| Language: English |
| Reprint Address: Krause, DS (reprint author), Yale Univ, Sch Med, Dept Lab Med, 333 Cedar St, New Haven, CT 06520 USA |
Addresses:
1. Yale Univ, Sch Med, Dept Lab Med, New Haven, CT 06520 USA |
| Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 USA |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: 834BG |
| ISSN: 0036-8075 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |