| | |  | | | | Record from Web of Science® | | | | | | |
| The general, practice research database - Role in pharmacovigilance |
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| Author(s): Wood L, Martinez C |
| Source: DRUG SAFETY Volume: 27 Issue: 12 Pages: 871-881 Published: 2004 |
| Times Cited: 51 References: 57 |
| Abstract: The General Practice Research Database (GPRD) is the world's largest computerised database of anonymised longitudinal clinical records from primary care. The database already has an international reputation in the field of drug safety signal evaluation where the results of GPRD-based pharmacoepidemiological studies have been used to inform regulatory pharmacovigilance decision making., The characteristics and richness of the data are such that the GPRD is likely to prove a key data resource for the proactive pharmacovigilance anticipated in risk management and pharmacovigilance plans. An update of recent developments to the database and new data available from it - including spontaneously recorded suspected adverse drug reactions - is presented in the article, with a description of how the data can be used to support a variety of pharmacovigilance applications. The possibility of using the GPRD in signal detection and assessment of the impact of pharmacovigilance activities in the future is also discussed.
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| Document Type: Article |
| Language: English |
| Reprint Address: Wood, L (reprint author), GPRD Div, Med & Healthcare Prod Regulatory Agcy, Room 15-103 Market Towers,1 9 Elms Lane,Vauxhall, London SW8 5NQ, England |
Addresses:
1. GPRD Div, Med & Healthcare Prod Regulatory Agcy, London SW8 5NQ, England |
| Publisher: ADIS INTERNATIONAL LTD, 41 CENTORIAN DR, PRIVATE BAG 65901, MAIRANGI BAY, AUCKLAND 10, NEW ZEALAND |
| Subject Category: Public, Environmental & Occupational Health; Pharmacology & Pharmacy; Toxicology |
| IDS Number: 860XX |
| ISSN: 0114-5916 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |