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Splenic rupture in a parental donor undergoing peripheral blood progenitor cell mobilization
Author(s): Dincer AP, Gottschall J, Margolis DA
Source: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY    Volume: 26    Issue: 11    Pages: 761-763    Published: NOV 2004  
Times Cited: 17     References: 12     
Abstract: Peripheral blood progenitor cells (PBPCs) are now widely used as a source of progenitor cells for allogeneic transplantation. Recombinant human granulocyte colony-stimulating factor is used to mobilize PBPCs for collection by leukapheresis. Although side effects of mobilization are generally benign, adverse effects have been reported. The authors present a case of spontaneous splenic rupture, without splenomegaly, in a parental donor undergoing PBPC mobilization, review the literature regarding this adverse event, and explore issues regarding donor safety.
Document Type: Article
Language: English
Reprint Address: Dincer, AP (reprint author), Med Coll Wisconsin, Div Neoplast Dis & Related Disorders, Dept Med, 9200 W Wisconsin Ave, Milwaukee, WI 53226 USA
Addresses:
1. Med Coll Wisconsin, Div Neoplast Dis & Related Disorders, Dept Med, Milwaukee, WI 53226 USA
2. Med Coll Wisconsin, Dept Pediat, Milwaukee, WI 53226 USA
Publisher: LIPPINCOTT WILLIAMS & WILKINS, 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
Subject Category: Oncology; Hematology; Pediatrics
IDS Number: 874FR
ISSN: 1077-4114
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