| | |  | | | | Record from Web of Science® | | | | | | |
| Kinetics of cytomegalovirus load decrease in solid-organ transplant recipients after preemptive therapy with valganciclovir |
|
|
| Author(s): Mattes FM, Hainsworth EG, Hassan-Walker AF, Burroughs AK, Sweny P, Griffiths PD, Emery VC |
| Source: JOURNAL OF INFECTIOUS DISEASES Volume: 191 Issue: 1 Pages: 89-92 Published: JAN 1 2005 |
| Times Cited: 34 References: 15 |
| Abstract: The availability of valganciclovir (VGCV) has significantly simplified the treatment of human cytomegalovirus (HCMV) infection after solid-organ transplantation. We show that there was no difference in the kinetics of the decrease in HCMV load after preemptive therapy with VGCV in 22 solid-organ transplant recipients (T-1/2 = 2.16 days), compared with that in 23 patients treated with intravenous ganciclovir (GCV) (T-1/2 = 1.73 days; P = .63). Preemptive therapy with VGCV pro vides control of HCMV replication that is comparable to that achieved with preemptive intravenous therapy with GCV. |
| Document Type: Article |
| Language: English |
| Reprint Address: Emery, VC (reprint author), UCL Royal Free & Univ Coll Med Sch, Div Infect & Immun, Ctr Virol, Rowland Hill St, London NW3 2QG, England |
Addresses:
1. UCL Royal Free & Univ Coll Med Sch, Div Infect & Immun, Ctr Virol, London NW3 2QG, England
2. UCL Royal Free & Univ Coll Med Sch, Liver Transplant Unit, London, England
3. UCL Royal Free & Univ Coll Med Sch, Renal Transplant Unit, London, England |
| Publisher: UNIV CHICAGO PRESS, 1427 E 60TH ST, CHICAGO, IL 60637-2954 USA |
| Subject Category: Infectious Diseases |
| IDS Number: 877JF |
| ISSN: 0022-1899 |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |