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The genetic theory of adaptation: A brief history
Author(s): Orr HA
Source: NATURE REVIEWS GENETICS    Volume: 6    Issue: 2    Pages: 119-127    Published: FEB 2005  
Times Cited: 141     References: 111     
Abstract: Theoretical studies of adaptation have exploded over the past decade. This work has been inspired by recent, surprising findings in the experimental study of adaptation. For example, morphological evolution sometimes involves a modest number of genetic changes, with some individual changes having a large effect on the phenotype or fitness. Here I survey the history of adaptation theory, focusing on the rise and fall of various views over the past century and the reasons for the slow development of a mature theory of adaptation. I also discuss the challenges that face contemporary theories of adaptation.
Document Type: Review
Language: English
Reprint Address: Orr, HA (reprint author), Univ Rochester, Dept Biol, Rochester, NY 14627 USA
Addresses:
1. Univ Rochester, Dept Biol, Rochester, NY 14627 USA
Publisher: NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
Subject Category: Genetics & Heredity
IDS Number: 893LT
ISSN: 1471-0056
DOI: 10.1038/nrg1523
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