| | |  | | | | Record from Web of Science® | |  |  | | |  |
| Global properties of biological networks |
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| Author(s): Grigorov MG |
| Source: DRUG DISCOVERY TODAY Volume: 10 Issue: 5 Pages: 365-372 Published: MAR 1 2005 |
| Times Cited: 21 References: 78 |
| Abstract: This article discusses the most recent achievements in understanding the biological implications of the small-world and scale-free global topological properties of genetic, proteomic and metabolic networks. Most importantly, these networks are highly clustered and have small node-to-node distances. With their few very connected nodes, which are statistically unlikely to fail under random conditions, the proper functioning of these systems is maintained under external perturbations. |
| Document Type: Review |
| Language: English |
| Reprint Address: Grigorov, MG (reprint author), Nestle Res Ctr, CH-1000 Lausanne 26, Switzerland |
Addresses:
1. Nestle Res Ctr, CH-1000 Lausanne 26, Switzerland |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND |
| Subject Category: Pharmacology & Pharmacy |
| IDS Number: 900WQ |
| ISSN: 1359-6446 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |