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| Camptocormia - Pathogenesis, classification, and response to therapy |
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| Author(s): Azher SN, Jankovic J |
| Source: NEUROLOGY Volume: 65 Issue: 3 Pages: 355-359 Published: AUG 9 2005 |
| Times Cited: 49 References: 60 |
| Abstract: Originally considered a psychogenic disorder, camptocormia, an abnormal posture with marked flexion of thoracolumbar spine that abates in the recumbent position, is becoming an increasingly recognized feature of parkinsonian and dystonic disorders. Prior reports were limited by sample size, short follow-up, and paucity of data on response to therapy. The authors reviewed 16 patients evaluated in their PD Center and Movement Disorders Clinic diagnosed with camptocormia. In addition to detailed neurologic assessment all patients were videotaped. The mean age was 64.9 +/- 17.4 years, mean age at onset of neurologic symptoms was 51.5 +/- 19.9 years, duration from onset of neurologic symptoms to development of camptocormia was 6.7 +/- 7.6 years, and the mean duration of camptocormia was 4.5 +/- 3.9 years. Of the 16 patients, 11 (68.8%) had Parkinson disease (PD); others had dystonia (n = 4) and Tourette syndrome (n = 1). Twelve patients received levodopa, with minimal or no improvement in the camptocormia. Nine patients received botulinum toxin type A injections into the rectus abdominus, with notable improvement in their camptocormia in four. One patient underwent bilateral subthalamic nucleus deep brain stimulation for PD, but there was no improvement in camptocormia. Based on this series and a thorough review of the literature of camptocormia, head drop, and bent spine syndrome, the authors propose etiologic classification of camptocormia and conclude that this heterogeneous disorder has multiple etiologies and variable response to systemic and local therapies. |
| Document Type: Review |
| Language: English |
| Reprint Address: Jankovic, J (reprint author), Baylor Coll Med, Dept Neurol, Director Parkinsons Dis Ctr & Movement Disorders, 6550 Fannin,Suite 1801, Houston, TX 77030 USA |
Addresses:
1. Baylor Coll Med, Dept Neurol, Director Parkinsons Dis Ctr & Movement Disorders, Houston, TX 77030 USA |
| Publisher: LIPPINCOTT WILLIAMS & WILKINS, 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA |
| Subject Category: Clinical Neurology |
| IDS Number: 953HM |
| ISSN: 0028-3878 |
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