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| Antimicrobial prophylaxis in allogeneic bone marrow transplantation. Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Haematology and Oncology |
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| Author(s): Kruger WH, Bohlius J, Cornely OA, Einsele H, Hebart H, Massenkeil G, Schuttrumpf S, Silling G, Ullmann AJ, Waldschmidt DT, Wolf HH |
| Source: ANNALS OF ONCOLOGY Volume: 16 Issue: 8 Pages: 1381-1390 Published: AUG 2005 |
| Times Cited: 11 References: 94 |
| Abstract: Patients undergoing allogeneic stem cell transplantation are at high risk for infection with a variety of pathogens during different phases of the procedure. Bacteria and fungi predominate the first phase until engraftment. During the second phase, from engraftment to about day 100, major infectious problems are caused by fungi and cytomegalovirus. Both pathogens remain important under continued immunosuppression, however, in the late post-transplantation period infections with encapsulated bacteria may become a problem. In this review the Infectious Diseases Working Party of the DGHO gives recommendations for prophylaxis of infections under allogeneic stem cell transplantation with drugs and other measures. The aim of the group was to do this on an evidence-based-medicine rating, if possible. |
| Document Type: Article |
| Language: English |
| Reprint Address: Kruger, WH (reprint author), Univ Greifswald, Med Klin Hamatol & Onkol C, Transplantat Zentrum, Ferdinand Sauerbruch Str, D-17487 Greifswald, Germany |
Addresses:
1. Med Klin C, Greifswald, Germany
2. Klinikum Univ Koln, Innere Med Klin 1, Cologne, Germany
3. Univ Tubingen, Med Klin 2, Abt Hamatol Onkol Immunol, Tubingen, Germany
4. Univ Klin Charite, Klin Hamatol & Onkol, Berlin, Germany
5. Univ Gottingen, Zentrum Innere Med, Hamatol Onkol Abt, D-3400 Gottingen, Germany
6. Univ Munster, KMT Zentrum, Med Klin A, D-4400 Munster, Germany
7. Univ Mainz Klinikum, Med Klin & Poliklin, Mainz, Germany
8. Klinikum Univ Koln, Klin Innere Med 4, Cologne, Germany
9. Univ Halle Wittenberg, Klin Innere Med 4, Halle Saale, Germany |
| Publisher: OXFORD UNIV PRESS, GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND |
| Subject Category: Oncology |
| IDS Number: 955LX |
| ISSN: 0923-7534 |
| DOI: 10.1093/annonc/mdi238 |
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