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| Persistent symptomless human metapneumovirus infection in hematopoietic stem cell transplant recipients |
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| Author(s): Debiaggi M (Debiaggi, Maurizia), Canducci F (Canducci, Filippo), Sampaolo M (Sampaolo, Michela), Marinozzi MC (Marinozzi, Maria Chiara), Parea M (Parea, Maurizio), Terulla C (Terulla, Cristina), Colombo AA (Colombo, Anna Amelia), Alessandrino EP (Alessandrino, Emilio Paolo), Bragotti LZ (Bragotti, Letizia Zenone), Arghittu M (Arghittu, Milena), Goglio A (Goglio, Antonio), Migliavacca R (Migliavacca, Roberta), Romero E (Romero, Egidio), Clementi M (Clementi, Massimo) |
| Source: JOURNAL OF INFECTIOUS DISEASES Volume: 194 Issue: 4 Pages: 474-478 Published: AUG 15 2006 |
| Times Cited: 29 References: 11 |
| Abstract: Sequential nasopharyngeal aspirates from patients without respiratory symptoms undergoing hematopoietic stem cell transplantation (HSCT) were tested for genomic RNA of human metapneumovirus (hMPV). Persistent hMPV infection was documented in most of them and confirmed by virus isolation. hMPV infection etiology was also evaluated during the same period in samples from pediatric patients with acute respiratory diseases (ARDs). Sequence analysis of hMPV in HSCT recipients documented infection by hMPV genotype A and strong interhost similarity; this pattern differs from that observed in pediatric patients with ARDs. The data indicate that HSCT recipients may frequently develop symptomless hMPV infection. |
| Document Type: Proceedings Paper |
| Language: English |
| Reprint Address: Debiaggi, M (reprint author), Univ Pavia, Dipartimento Sci Morfol Eidol & Clin, Sez Microbiol, Via Brambilla 74, I-27100 Pavia, Italy |
Addresses:
1. Univ Pavia, Dipartimento Sci Morfol Eidol & Clin, Sez Microbiol, I-27100 Pavia, Italy
2. Policlin San Matteo, Ist Ricovero & Cura Carattere Sci, Serv Anal Microbiol, Pavia, Italy
3. Policlin San Matteo, Ist Ricovero & Cura Carattere Sci, Ctr Trapianti Midollo Osseo, Div Ematol, Pavia, Italy
4. Ist Ricovero & Cura Carattere Sci San Raffaele, Lab Microbiol & Virol, Milan, Italy
5. Univ Vita Salute San Raffaele, Milan, Italy
6. Presidio Vizzolo Predabissi, Azienda Osped Melegnano, Bergamo, Italy
7. Osped Riuniti Bergamo, Bergamo, Italy |
| Publisher: UNIV CHICAGO PRESS, 1427 E 60TH ST, CHICAGO, IL 60637-2954 USA |
| Subject Category: Infectious Diseases |
| IDS Number: 064WO |
| ISSN: 0022-1899 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |