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Modulating the outer membrane with small RNAs
Author(s): Guillier M (Guillier, Maude), Gottesman S (Gottesman, Susan), Storz G (Storz, Gisela)
Source: GENES & DEVELOPMENT    Volume: 20    Issue: 17    Pages: 2338-2348    Published: SEP 1 2006  
Times Cited: 55     References: 62     
Abstract: MicF, one of the first chromosomally encoded regulatory small RNAs (sRNAs) to be discovered, was found to modulate the expression of OmpF, an abundant outer membrane protein. Several recent papers have now shown that this is not an isolated case. At least five other sRNAs also regulate the synthesis of outer membrane porins, and additional sRNAs modulate the expression of other outer membrane proteins. Here we review what is known about these sRNAs and discuss the implications of this regulation.
Document Type: Review
Language: English
Reprint Address: Gottesman, S (reprint author), NCI, Mol Biol Lab, Bldg 37, Bethesda, MD 20892 USA
Addresses:
1. NCI, Mol Biol Lab, Bethesda, MD 20892 USA
2. NICHHD, Cell Biol & Metab Branch, Bethesda, MD 20892 USA
Publisher: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2924 USA
Subject Category: Cell Biology; Developmental Biology; Genetics & Heredity
IDS Number: 081FU
ISSN: 0890-9369
DOI: 10.1101/gad.1457506
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